Hyderquin plus cream (15gm) and Tri-Melasin (30gm) are both topical creams specially made to treat melasma. It is recommended for both long and short-term use, and for individuals with mild to severe dark spots. The triple combination formula is extremely beneficial for treating dark spots associated with moderate to severe facial melasma. The three main active ingredients in Hyderquin plus cream and Tri-Melasin cream are 4% hydroquinone, 0.05% tretinoin, and 0.1% Fluocinolone Acetonide (TRILUMA ingredients). Hydroquinone is the top ingredient found in many effective topical preparations and is extremely effective in lightening skin. This active ingredient inhibits melanin production to successfully fade dark spots, freckles, sun damage, melasma, and even acne scars. By combining Hydroquinone with another skincare ingredient Tretinoin, a vitamin A derivative, Hyderquin plus cream and Tri-Melasin cream provides skin lightening effects and anti-aging benefits. Tretinoin 0.05% works by increasing the skin cell turnover rate, which helps exfoliate the skin.